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Cleveland, Ohio clinic performs US’s first face transplant

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

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Galloway and Pasqua deny any wrongdoing on their part in the oil-for-food program

Tuesday, May 17, 2005

Following accusations issued by the United States Senate Permanent Subcommittee on Investigations (PSI), British Member of Parliament George Galloway and Senator Charles Pasqua of France have vehemently denied any wrongdoing.

George Galloway declared:

I’ve now had a chance to read the report which was compiled without this Senate committee asking me a single question about these absurd allegations. I repeat once more. I have never traded or benefited from any oil deals with Iraq.

One of the companies named, with ostensible links to me– Aredio Petroleum– I have never heard of until today and I have certainly had no dealings with. The other company, Middle East Advanced Semiconductors, was owned by Fawaz Zureikat, who was the chairman of the Mariam Appeal. It is well-known that Mr Zureikat traded with Iraq but he did not do so on my behalf. I have not received a penny piece or any oil voucher from Iraq, directly or indirectly.

You would have thought that natural justice would have demanded that these allegations would have– must have been!– put to me, but they haven’t been. Senator Joseph McCarthy would have been proud of this committee.

On May 17, Galloway appeared before the U.S. senatorial panel and vehemently denied any wrongdoing in a tone seldom used in a senatorial hearing. He accused the U.S. administration of creating a “smoke screen” to divert attention away from the situation in Iraq. He also declared, “The biggest sanctions busters were not me or Russian politicians or French politicians. The real sanctions busters were your own companies with the connivance of your own government.”

Galloway denied receiving any money out of the scheme. Galloway demanded, “What counts is, where’s the money, senator? Who paid me hundreds of thousands of dollars? The answer to that is nobody,” while glaring toward U.S. senator Norm Coleman (Republican from Minnesota), according to a New York Times report.

Galloway also accused the US senators, especially senator Coleman, of shoddy standards of justice. He claimed they have already ruled him guilty, and that they rely on dubious evidence and wrongful or coerced testimonies.

Galloway declared:

You have my name on lists provided to you… by the convicted bank robber and fraudster and con man Ahmed Chalabi, who many people, to their credit, in your country now realize played a decisive role in leading your country into the disaster in Iraq.

In these circumstances, knowing what the world knows about how you treat prisoners in Abu Ghraib prison1, in Bagram Air Base [Afghanistan], in Guantanamo Bay — including, if I may say, British citizens being held in those places — I’m not sure how much credibility anyone would put on anything you manage to get from a prisoner in those circumstances.

1. Alluding to the acknowledged Abu Ghraib torture and prisoner abuse.

Charles Pasqua also denies any personal wrongdoing in the case. Pasqua indicated that he was “serene” and that he hoped the investigations by the U.S. Senate would probe the matter to the bottom.

Pasqua judged the situation detrimental to relationships between the United States and France. For this reason, Pasqua declared that he had asked the president of the French Senate for the creation of an investigation commission, wishing that the French and U.S. senatorial commissions should collaborate.

Pasqua declared himself convinced that misconduct took place in the oil-for-food program, and that it was probable that some French people were involved. He then wished that they should be sought and prosecuted. “If one wants to find the origin of the financial streams, one can do so.” Pasqua mentioned the Swiss company Genmar, which the U.S. report claims to have served as Pasqua’s intermediary.

Pasqua denied information presented as facts in the report. For instance, he denied having met Tariq Aziz, former Deputy Prime Minister of Iraq.

Pasqua pointed out that nothing in the senatorial evidence indicates that he had benefited from vouchers, only that one of his former advisers, Bernard Guillet, had received oil allocations in his name. From December 2000 onwards, allocations meant for Pasqua ceased and were replaced by allocations to Bernard Guillet.

Guillet was arrested by French authorities in April in connection with abuses under the oil-for-food program. Mr Guillet has been put under formal investigation for allegedly participating in a system of occult kickbacks and fees between 1996 and 2001 involving major French companies, including Total. He is suspected of having received amounts of money without good explanation from an intermediary specialized in the resale of Iraqi oil.

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Strongest earthquake in 40 years hits Southeast Asia

Sunday, December 26, 2004

Indian Ocean – The death toll continues to grow and millions face a homeless life in the new year as coastal communities in south Asia struggle against continued aftershocks and flooding caused by the largest earthquake to strike the planet in more than a generation.

The magnitude 9.0 undersea megathrust earthquake struck off the western coast of Sumatra, Indonesia on December 26, 2004, at 00:58:50 UTC (or 07:58:50 local time in Jakarta and Bangkok).

The earthquake was the strongest in the world since the 9.2-magnitude Good Friday Earthquake which struck Alaska, USA in 1964, and the fourth largest since 1900. More than 140,000 deaths[1] were caused by resulting tsunami, which in Thailand were up to 10 meters (33 feet) tall, and struck within three hours of the initial event.

Multiple tsunamis struck and ravaged coastal regions all over the Indian Ocean, devastating regions including the Indonesian province of Aceh, the coast of Sri Lanka, coastal areas of the Indian state of Tamil Nadu, the resort island of Phuket, Thailand, and even as far away as Somalia, 4,100 km (2,500 mi) west of the epicenter.

While the earthquake and the tsunamis are no longer ongoing (other than aftershocks), the humanitarian and economic crisis generated by the disaster is still ongoing. This report will attempt to cover the crisis as it continues to develop.

Contents

  • 1 Damage and casualties
  • 2 Quake characteristics
  • 3 Post-tsunami humanitarian situation
    • 3.1 Humanitarian assistance
  • 4 Related news
  • 5 See also
  • 6 External links
    • 6.1 Aid efforts
    • 6.2 Video and Pictures of the devastation
  • 7 Video
  • 8 Pictures
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Flash floods hit Australia’s eastern coast

Thursday, June 30, 2005

6,000 residents of Lismore in NSW have been told to evacuate their homes.

A couple is missing on the Gold Coast in Queensland. State Emergency Services (SES) workers are currently preparing to evacuate a number of nursing homes in the suburbs of Southport and Burleigh.

The Australian Bureau of Meteorology (BOM) have said that South East Queensland has recorded rainfalls of 368mm in the last 24 hours and that the Gold Coast suburb of Coolangatta has been averaging 80mm per hour for at least two hours. The Coolangatta airport was closed due to flooding.

Further south the city of Lismore has been inundated. A recently constructed levy has held back the waters of the Wilson river, protecting the town’s central business district.

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Adam Folkard and Nick Norton ready for more men’s softball

Monday, March 19, 2012Hawker, Canberra — Coming off a national championship win for the Australian Capital Territory (ACT) men’s open team in mid-February, Australia men’s national softball team representatives Nick Norton and Adam Folkard are getting ready for more softball later this year, including the Australian club championships to be held in Brisbane in June.

Folkard and Norton have both won the World Championships and have each won a total of ten national championships with the ACT side. They are both named to the current men’s national team, which has roughly thirty players, and believe they are likely to survive the December cut down to eighteen players who will represent Australia at next year’s World Championship in Auckland, New Zealand.

The World Championship is one of the two most prestigious available to male softball players. The other is the International Softball Congress, an event Folkard and Norton have both competed at.

As national team representatives, there are a lot of expectations for them. In Australia, there is almost no financial support for the men’s game so they must cover most of their own costs, including travel to and from international competitions. According to Folkard’s father, these costs can be prohibitive. In one year, when Folkard was a representative on the men’s U18, U23 and Open team, it cost A$15,000 for travel and other expenses just for Folkard. When costs for bringing family members such as Folkard’s sisters to major international tournaments, the costs were even higher. Folkard, his father and Norton all joked this cost his father an investment property to allow Folkard to continue to compete at the highest level. Both Folkard and Norton currently work as tradesmen to support softball playing.

Beyond money, the national team requires players to be actively involved in wider softball community. Players must represent a club at the club championships in Brisbane if they want to retain a spot in the squad. Folkard plays for a Western Australian club and Norton plays for a Sydney based club, driving down from Canberra to play every Sunday during the season.

Folkard and Norton have both played softball at the highest level in the United States, where the men’s game is not yet fully professionalized but still presents more opportunities for players than are available at home. For several years, Folkard has gone to the United States for three-month stints, playing for teams in Chicago, Pennsylvania, and New York. One side he played was sponsored by Ernst and Young. Folkard currently plays for a Canadian side and has been trying to convince Norton, whom he has grown up playing softball with, to join him like Norton has done one previous season. According to Folkard, playing with a North American club has certain advantages. The clubs pay for his travel to and from Australia, and pay for Championship rings. When asked how North American clubs sign Australian players, he said they follow men’s softball in Australia and call up players to offer contracts. Australian men’s players gain additional exposure to potential clubs when they compete, with some sides approaching them during the North American season and seeking to contract them for the following season.

Both men would love the opportunity to play softball in the Olympics, but believe such an opportunity is unlikely. According to them, softball at the Olympics is a women’s game intrinsically linked to men’s baseball, and men’s softball is unlikely to ever be considered on the programme as a result.

Folkard and Norton both play for the same club in the ACT territory club competition. Their team has secured a grand final berth for the match in ten days. They are waiting to find out who they will play against based on a match this weekend. Both have previously won this competition.

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European Space Agency seeks volunteers for Mars simulation

Thursday, June 28, 2007

The European Space Agency (ESA) is seeking volunteers who would be ready to take a part on three simulated missions to Mars.

The anticipated missions will be a joint effort from ESA and the Russian Federal Space Agency. Each crew will consist of six persons – two Europeans and four Russians. The ESA is looking for 2 crewmembers and two backups that must come from ESA member nations that participate in the ELIPS program.

The flight simulation should last between 105 to 520 days in a closed modules set of total space of 500 . The goal of the mission is to test the psychological stress of the long-distance travel. To make the experience as realistic as possible, the contact with the external world shall exist only via the radio with a time-delay of 40 minutes (simulating the time required for signals to travel between the Earth and Mars).

The first test of 105 days should start in middle of 2008 and the last one should start at the end 2008 or the beginning of 2009.

Interested persons can apply via an application form published on the ESA website.

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G20 protester dies after collapsing

Wednesday, April 1, 2009

According to reports, a man protesting the G20 Summit in London, England has died after collapsing at a protester camp.

Sky News says the man collapsed on the street inside a camp close to the Bank of England and when found he was still breathing, but efforts by paramedics to rescue him failed and he was pronounced dead at an area hospital. The name of the person and cause of death are not yet known, but several people were injured earlier in the day. The police claim that protestors threw bottles at them while trying to rescue the protestor.

The London Ambulance Service reported that “we received a 999 call at 7:24 pm from a member of the public reporting that a man had fallen over and was unconscious, but was breathing. [They] made extensive efforts to resuscitate him both there and on the way to hospital.”

Earlier in the day a minimum of 20 protesters broke into the bank and according to reports vandalized furniture, broke windows and cut the telephone lines to the building.

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US clinic plans first face transplant

Tuesday, September 20, 2005

US doctors are to interview 12 patients with a view to performing the first ever transplant of a human face.

The Cleveland Clinic will choose between seven women and five men to find the person most suited for the experimental procedure, which is a radical and controversial solution to extreme facial scarring or disfigurement.

Having practiced the procedure on bodies donated for medical research, the Cleveland Clinic team believe they have a 50% chance of success. The procedure will not live up to science-fiction predictions and give the recipient the appearance of the donor; the underlying bone structure is the deciding factor in the final appearance. The new face will end up resembling neither the donor nor recipient.

Surgeons in several other countries have announced being ready to perform this procedure in the past. However, the risk and non life-threatening nature of disfigurement have meant that gaining approval for the groundbreaking surgery has been difficult. Like many other transplant operations, the recipient would be required to take drugs to prevent tissue rejection for the remainder of their life. These drugs can have side effects and carry their own risks involving the patient’s immune system.

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On the campaign trail in the USA, October 2016

Sunday, November 6, 2016

The following is the sixth and final edition of a monthly series chronicling the U.S. 2016 presidential election. It features original material compiled throughout the previous month after an overview of the month’s biggest stories.

In this month’s edition on the campaign trail: the Free & Equal Foundation holds a presidential debate with three little-known candidates; three additional candidates give their final pleas to voters; and past Wikinews interviewees provide their electoral predictions ahead of the November 8 election.

Contents

  • 1 Summary
  • 2 Free & Equal Debate
  • 3 Final pleas
  • 4 Predictions
  • 5 Related articles
  • 6 Sources
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Psychiatrist Dr. Jerald Block tells Wikinews about addiction to the Internet

Wednesday, October 22, 2008

Dr. Jerald Block is a psychiatrist based in Portland, Oregon, United States. Dr. Block has attracted some media attention due to one theory of his – the idea that Internet addiction can be viewed as a distinct mental condition.

In an interview with Wikinews, Dr. Block discusses this theory, including what needs to be done about it, and the alleged violent response that can arise from an addict’s withdrawal. Below is the full exclusive interview.